Quoth the film's official site:
During a stopover in Germany in the middle of a carefree roadtrip through Europe, two American girls find themselves alone at night when their car breaks down in the woods. Searching for help at a nearby villa, they are wooed into the clutches of a deranged retired surgeon who explains his mad scientific vision to his captives' utter horror. They are to be the subjects of his sick lifetime fantasy: to be the first to connect people, one to the next, via their gastric system, and in doing so bring to life 'the human centipede.'
Check out the trailer below.
Apparently this doctor has never heard the old adage, "You never go ass to mouth." It will be interesting to see if the movie maintains the horror or if it relies solely on the admittedly disturbing premise. It will also be interesting to see if there's any videogame tie-in.